Preclinical disease models
Our preclinical studies are built on the 3Rs principles—Replacement, Reduction, and Refinement—guiding every procedure to minimize impact while maximizing scientific value
Disease models

To support our customers in conducting high-quality and ethically responsible research, we offer comprehensive guidance in:
- Project planning & study design – Helping you design robust preclinical studies tailored to your research objectives
- Selection of animal models – Advising on the most relevant models to ensure translational value and scientific validity
- Protocol development & optimization – Leveraging our scientific expertise to refine experimental protocols, optimize imaging workflows, and ensure data quality and reproducibility
- Regulatory compliance & consultation – Ensuring adherence to ethical guidelines, promoting the principles of the 3Rs (Replacement, Reduction, Refinement), and assisting with applications for animal study approvals
Ethical statement
At OITL, animal welfare and ethical research are paramount. We adhere to strict regulations and legal standards, based on the EU Directive 2010/63/EU on the protection of animals used for scientific purposes, ensuring the highest level of care.